Title: Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia: insights from a RyR2^R4496C+/- knock-in mouse model. HEART RHYTHM Society 2006 – Boston 17-20 2006 Abstract presentation   [AB23-1]. Oral Abstract Sessions: BASIC/TRANSLATIONAL SCIENCE IV: Molecular Mechanisms Regulating Ion Channel Function.
Author: Nian Liu, Barbara Colombi, Mirella Memmi, Carlo Napolitano, Silvia G. Priori

Title: Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mouse model carrier of calsequestrin R33Q mutation. 4. HEART RHYTHM Society 2008 - [2008] [AB28-5]
Author: Nian Liu, Nicoletta Rizzi, Barbara Colombi, Luca Boveri, Carlo Napolitano, Silvia G Priori

Title: FKBP12.6 Binding Characteristics of Ryanodine Receptor Mutations Associated with Arrhythmogenic Cardiac Disease. Annual Meeting of the Biophysical Society, Boston, USA, February 2009, Biophysical Journal 96(3) pp. 111a.
Author: S. Zissimopoulos, N.L. Thomas, F.A. Lai.

Title: G1885E RyR2 Polymorphism Modulates The Caffeine Sensitivity Of An Arrhythmia-linked Mutation. Annual Meeting of the Biophysical Society, Boston, USA, February 2009, Biophysical Journal 96(3) pp. 111a.
Author: A.I. Clack, N.L. Thomas, C.H. George, F.A. Lai.

Title: Targeted Stabilisation Of The RyR2 I-Domain Restores Ca²⁺ Handling And Intercellular Synchrony In Ouabain-disrupted Cardiac Cell Monolayers. Annual Meeting of the Biophysical Society, Boston, USA, February 2009, Biophysical Journal 96(3), pp. 113a.
Author: H. Jundi, F.A. Lai, C.H. George

Title:  Decoding The Molecular Basis Of Anti-Apoptotic Cardiac Ca²⁺ Signalling Via Human RyR2 Splice Variants. Annual Meeting of the Biophysical Society, Boston, USA, February 2009, Biophysical Journal 96(3) pp. 111a - 112a.
Author: W.Y. Yeung, M. Davies, F.A. Lai, A.J. Williams, C.H. George.

Title: Ryanodine Receptor Phosphorylation by Protein Kinase A Alters the Affinity for FKBP12. Annual Meeting of the Biophysical Society, Boston, USA, February 2009, Biophysical Journal 96(3) pp. 108a.
Author: J. Griffiths, J.L. Jones, F.A. Lai, L. Blayney.

Title: An L433P Arrhythmia-linked Mutation In RyR2 Uncouples Agonist-evoked Ca²⁺ Release From Homeostatic Ca²⁺ Cycling. Annual Meeting of the Biophysical Society, Boston, USA, February 2009, Biophysical Journal 96(3) pp. 111a.
Author: A.I. Clack, D.L. Fry, N.L. Thomas, F.A. Lai, C.H. George.

Title: Investigating the Ca²⁺-Cycling Basis of Rhythmicity and Synchronicity in Coupled Cardiomyocyte Monolayers. Annual Meeting of the Biophysical Society, Boston, USA, February 2009, Biophysical Journal 96(3) pp. 273a - 274a.
Author: N.C. Silvester, S.R. Barberini-Jammaers, P.M. Ashton, A. Jayanthi, W.Y. Yeung, H. Jundi, A. Kotecha, F.A. Lai, C.H. George.

Title: Serum factors promote RyR2 molecular instability and Ca²⁺ release dysfunction. European Society of Cardiology (ESC) Heart Failure Winter Research Meeting on Translational Cardiology – Les Diablerets, SWITZERLAND, January 2009. Final Programme and Abstract Book 2009.
Author: C.H. George, S.R. Barberini, W.Y. Yeung, R. Bloise, C. Napolitano, S.G. Priori, F.A. Lai.

Title: SALVO - A new analytical platform for decoding intracellular Ca²⁺ fluxes and evaluating anti-arrhythmic compounds. Annual Meeting of the Biophysical Society, Long Beach, USA, March 2008.
Author: S.R. Barberini, P.M. Ashton, W.C. Claycomb, F.A. Lai, C.H. George.

Title: Suppression of arrhythmogenic Ca²⁺ fluxes in cardiac cells using fragments of human RyR2. Annual Meeting of the Biophysical Society, Long Beach, USA, March 2008.
Author: H. Jundi, D.L. Fry, S.R. Barberini, F.A. Lai, C.H. George.

Title: Mutation-linked structural instability underlies RyR2 channel hypersensitivity to serum-borne factors. Annual Meeting of the Biophysical Society, Long Beach, USA, March 2008.
Author: C.H. George, W.Y. Yeung, S.R. Barberini, N. Walters, R. Bloise, C. Napolitano, S.G. Priori, AJ. Williams, F.A. Lai.

Title: Modulating intracellular Ca²⁺ signaling using recombinant fragments of the human cardiac ryanodine receptor (RyR2). Annual Meeting of the Biophysical Society, Baltimore, USA, March 2007.
Author: NL Thomas, FA Lai, CH George

Title: Ryanodine receptor expression and phosphorylation in β-adrenoceptor-mediated arrhythmogenesis in human atrium. Annual Congress of the Austrian Cardiological Society (ÖKG) – Salzburg, AUSTRIA, June 2009. Journal für Kardiologie 16(5-6):160-2.
Author: Kockskämper J, Schottky D, Niazi M, Sigirci E, Wakula P, Lai FA, Deuter M, Brauer S, Seipelt R, Schöndube F, Oehlmann R, Pieske B.

Title: Cytosolic Na⁺ accumulation triggers arrhythmogenic events in murine ventricular myocytes harbouring a human CPVT mutation (RyR2^R4496C+/-). Annual Congress of the Austrian Cardiological Society (ÖKG) – Salzburg, AUSTRIA, June 2009. Journal für Kardiologie 16(5-6):165.
Author: Sedej S, Kockskämper J, Heinzel FR, Walther S, Dybkova N, Maier LS, Vos MA, Napolitano C, Priori SG, Pieske B.

Title: Na⁺-dependent sarcoplasmic reticulum Ca²⁺ overload elicits arrhythmogenic events in mouse ventricular myocytes with a human CPVT mutation – a protective role of JTV-519. Heart Failure 2009: Annual Congress of the Heart Failure Association of the European Society of Cardiology (ESC); Nice, FRANCE, May/June 2009. Eur. J. Heart Fail. Suppl. 8: Abstract 1367.
Author: Sedej S, Kockskämper J, Heinzel FR, Walther S, Dybkova N, Maier LS, Priori SG, Pieske B.

Title:  Na⁺-induced sarcoplasmic reticulum Ca²⁺ overload triggers arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation. Annual Congress of the German Society for Cardiology (DGK) – Mannheim, GERMANY, April 2009. Clin Res Cardiol 98:Suppl 1, V-616.
Author: Sedej S, Kockskämper J, Heinzel FR, Walther S, Groborz J, Gronau P, Dybkova N, Maier LS, Vos MA, Napolitano C, Priori SG, Pieske B.

Title: Ryanodine receptor expression and phosphorylation in β-adrenoceptor-mediated arrhythmogenesis in human atrium. Annual Congress of the German Society for Cardiology (DGK) – Mannheim, GERMANY, April 2009. Clin Res Cardiol 98:Suppl 1, V-619.
Author: Kockskämper J, Schottky D, Niazi M, Sigirci E, Wakula P, Lai FA, Deuter M, Brauer S, Seipelt R, Schöndube F, Oehlmann R, Pieske B.

Title:  JTV-519 reduces vulnerability to ouabain-induced arrythmogenic events in mouse ventricular myocytes with a human CPVT mutation. European Society of Cardiology (ESC) Heart Failure Winter Research Meeting on Translational Cardiology – Les Diablerets, SWITZERLAND, January 2009. Final Programme and Abstract Book 2009.
Author: Sedej S, Kockskämper J, Heinzel FR, Walther S, Dybkova N, Maier LS, Priori SG, Pieske B.

Title:  Increased vulnerability to ouabain-induced arrhythmias in myocytes from mouse hearts harboring a human CPVT mutation. Annual Congress of the German Society for Cardiology (DGK) – Mannheim, GERMANY, March 2008.Clin Res Cardiol 97:Suppl (1). P1530.
Author: Sedej S, Kockskämper J, Heinzel FR, Groborz J, Gronau P, Dybkova N, Maier LS, Colombi B, Napolitano C, Priori SG, Pieske B.

Title:  Overexpression of CaMKIIδc in RyR2^R4496C knock-in mice leads to spontaneous sudden cardiac death and altered intracellular Ca handling. Annual Congress of the German Society for Cardiology (DGK) – Mannheim, GERMANY, March 2008.Clin. Res. Cardiol. 97:Suppl (1). V49.
Author: Dybkova N, Napolitano C, Rokita A, Neef S, Hünlich M, Kockskämper J, Priori SG, Pieske B, Maier LS.

Title:  Increased vulnerability to ouabain-induced arrhythmias in myocytes from mouse hearts harboring a human CPVT mutation. Cardiovascular Research Days – Weissensee, Austria, January 2008.Eur. Surg. 40:Suppl (220), 10.
Author: Sedej S, Kockskämper J, Heinzel F, Groborz J, Gronau P, Dybkova N, Maier LS, Colombi B, Napolitano C, Priori SG, Pieske B.

Title: The capacity of the heart to withstand an arrhythmic challenge increases with flunarazine which can be quantified using beat-to-beat variability of repolarization. Conference abstract. European Society of Cardiology, Vienna, 2007
Author: Oros, G. Antoons, P. Oosterhoff, M.J.C. Houtman, N.J.M. Attevelt, J.D.M. Beekman, M.A. Vos.

Title: RyR-2 dysfunction associated to Catecholaminergic Polymorphic Ventricular Tachycardia. Molecular and Cellular Biology of Heart Failure. Azur Heart Meeting. Carry le Rouet - France, 1-3 June 2007.
Author: A-M Gomez, M. Fernandez-Velasco M, A. Rueda A, J-P. Benitah, B. Colombi, C. Napolitano, S. Priori, S. Richard.

Title: Modulation of calcium handling in RyR^(R4496C) mice. Biophysical Journal: 344A-344A Suppl. S Jan 2007.
Author: M. Fernandez-Velasco M, A. Rueda A, J-P. Benitah, B. Colombi, C. Napolitano, S. Priori, S. Richard, A-M Gomez.

Reference:
Abstract Title: Spontaneous action potentials in ventricular myocytes. Cascais, Portugal, 2-5 March 2009. Abstract, p. 6
Author: Alexandra Zahradníková, Elena Cocherová, Jana Pavelková, Ivan Zahradník

Title: Effect of ATP on the sensitivity of the cardiac ryanodine receptor and its impact on kinetics, dependent on Ca²⁺ conditions, Regional Biophysical Conference, Linz, Austria, 2009. Abstract book, p. 176
Author: B. Tencerová, A. Zahradníková, M. Gaburjaková.

Title: Effect of ATP on the sensitivity of the cardiac ryanodine receptor and its impact on kinetics with different luminal Ca²⁺ and cytosolic Ca²⁺. 85. Physiological Days, Prague, Czech Republic, 3-5 February 2009. Physiological Research, Vol. 58 (3), p.28, 2009
Author: B.Tencerová, J.Gaburjáková, A.Zahradníková, M.Gaburjáková

Reference:
Abstract Title: Generation and suppression of calcium-induced arrhythmias in a model of heart ventricular myocyte. 2nd workshop of the ESF research network 'FuncDyn', Rothenburg ob der Tauber, Germany, 15-18 September 2008. Abstracts of talks, p. 9-10
Author: E. Cocherová, J. Parulek, J. Pavelková, and A. Zahradníková.

Reference:
Abstract Title: A stochastic fire-diffuse-fire model of calcium sparks and waves in cardiac myocytes with allosterically gating ryanodine receptors. European Conference on Mathematical and Theoretical Biology, Edinburgh, United Kingdom, 29 June - 4 July 2008.
Author: I. Valent, I. Zahradník, A. Zahradníková.

Title: Effects of Changes of Ryanodine Receptor Gating on the Susceptibility to Arrhythmias in Heart Myocytes: a Modeling Study. Slovak Biophysical Symposium, Bratislava, Slovakia, 18-20 April 2008. Abstracts book, p. 53-54
Author: E. Cocherová, J. Parulek, A. Zahradníková

Title: The Effect of Altered Ryanodine Receptor Gating on Generation of Calcium Sparks and Propagation of Calcium Waves in a Cardiac Myocyte Model. Slovak Biophysical Symposium, Bratislava, Slovakia, 18-20 April 2008 Abstracts book, p. 16-17
Author: Ivan Valent, Ivan Zahradník and Alexandra Zahradníková

Title: Sensitivity of the cardiac ryanodine receptor to ATP and its impact on kinetics with different luminal Ca²⁺. Slovak Biophysical Symposium, Bratislava, Slovakia, 18-20 April 2008. Abstracts book, p. 20-21
Author: B. Tencerová, J. Gaburjáková, A. Zahradníková, M. Gaburjáková.

Title: Simulation of the effect of changed ionic conductances on the parameters of heart myocyte action potential. Proceedings of the Czech and Slovak Physiological Societies (84. Physiological Days), 6-8 February 2008, Martin, Slovakia, Physiological Research 57: 11P, 2008.
Author: Cocherová E., Zahradníková, A

Title: Effect of luminal Ca²⁺ on the sensitivity of the cardiac ryanodine receptor to ATP. Joint Meeting of the Slovak Physiological Society and The Physiological Society and The Federation of European Physiological Societies, Bratislava, 11.-14.9.2007.  PW01-4 Acta Physiologica Vol. 191 Suppl. 658, Sep 2007, p.55
Author: Tencerová B., Gaburjáková J., Zahradníková A., Gaburjáková M